منابع مشابه
Tenofovir-associated proteinuria.
Proteinuria was observed in 27% of 153 patients taking tenofovir for more than 1 year. Concomitant protease inhibitor therapy and cumulative tenofovir exposure were independently associated with proteinuria in this cohort. Proteinuria was reversible in 11 of 12 patients who ceased tenofovir because of proteinuria without altering other medications. Clinicians should be aware that tenofovir can ...
متن کاملTenofovir is associated with increased tubular proteinuria and asymptomatic renal tubular dysfunction in Ghana
BACKGROUND HIV infection is associated with increased risk of renal dysfunction, including tubular dysfunction (TD) related to antiretroviral therapy (ART). Tenofovir disoproxil fumarate (TDF) is becoming available for ART in sub-Saharan Africa, although data on its long-term safety there is limited. We aimed to study the prevalence of HIV-associated renal dysfunction in Ghana and explore assoc...
متن کاملTenofovir-associated bone density loss
Clinical observations have revealed a strong correlation between loss of bone density in HIV-infected individuals, particularly in conjunction with the antiretroviral drug tenofovir, a nucleotide analog that inhibits HIV reverse transcriptase. The most compelling correlations have been observed in clinical studies involving young children and adolescents. These observations strongly suggest tha...
متن کاملMicrofilariae-associated nephrotic range proteinuria.
A 50-year-old man presented with pedal edema and episodes of hematuria that had started 1 month before. Systemic examination revealed mild pedal edema and petechial rashes on both lower limbs, without lymphadenopathy. The urine color was noted to be milky white (Figure 1). Urine analysis showed 3þ albumin and numerous red blood cells. Urine spot protein creatinine ratio (PCR) was 14.8. Serum al...
متن کاملRenal tubular dysfunction associated with tenofovir therapy.
OBJECTIVE To describe the i ncidence a nd cha racteristics of Tenofovir (TDF) induced nephrotoxicity among people living with HIV AIDS (PLHA) receiving TDF based anti-retroviral therapy (ART) at Christian Medical College, Vellore. METHOD Medical record review of all the PLHA who is being enrolled and followed up at the ART clinic at CMC, Vellore. RESULTS From 2006-11, a total of 274 PLHA ha...
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ژورنال
عنوان ژورنال: AIDS
سال: 2013
ISSN: 0269-9370
DOI: 10.1097/qad.0b013e32835883bf